Sustainable Flow Synthesis of a Versatile Cyclopentenone Building Block
نویسندگان
چکیده
منابع مشابه
1-Hydroxymethyl-4-phenylsulfonybutadiene, a versatile building block for the synthesis of 2,3,4-trisusbtituted tetrahydrothiophenes.
A method to synthesize chiral 2,3,4-trisusbtituted tetrahydrothiophenes in both enantiomerically pure forms starting from 1-hydroxymethyl-4-phenylsulfonylbutadiene is described.
متن کامل(1-bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis.
Iterative cross-coupling represents a potentially general approach for the simple, efficient, and flexible construction of a wide range of functional small molecules. In this context, (1-bromovinyl)-N-methyliminodiacetic acid (MIDA) boronate is a very useful building block for small molecule synthesis. This compound can serve as a starting material for the preparation of a wide range of 1,1-dis...
متن کاملVinyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis
Iterative cross-coupling represents a potentially general approach for the simple, efficient, and flexible construction of natural products, pharmaceuticals, and materials. N-Methyliminodiacetic acid (MIDA) boronates represent a promising platform for the development of this type of synthesis strategy. This report describes the discovery that vinyl MIDA boronate (1) is an airand chromatographic...
متن کاملA versatile building block for pyrazole-pyrrole hybrid macrocycles.
This contribution describes the synthesis of a novel pyrazole-pyrrole building block and its use in the formation of a non-aromatic, Schiff base-type macrocycle incorporating a chromophore and H-bonding donor and acceptor functionalities inside and outside of the macrocycle, which makes it predestined for molecular recognition systems.
متن کاملEarthworm Is a Versatile and Sustainable Biocatalyst for Organic Synthesis
A crude extract of earthworms was used as an eco-friendly, environmentally benign, and easily accessible biocatalyst for various organic synthesis including the asymmetric direct aldol and Mannich reactions, Henry and Biginelli reactions, direct three-component aza-Diels-Alder reactions for the synthesis of isoquinuclidines, and domino reactions for the synthesis of coumarins. Most of these rea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Organic Process Research & Development
سال: 2017
ISSN: 1083-6160,1520-586X
DOI: 10.1021/acs.oprd.7b00328